Ethanolamine → HCID 44481634, compound

Participants

Reaction Steps

Preparation according to Example 22 using 2-(bromomethyl)-7-(methylsulfonyl)-4H-1,3-benzodioxine (30 mg, 0.10 mmol), 2-aminoethanol (0.5 ml, 24.9 mmol) and EtOH (1.0 ml). 1H-NMR (400 MHz, MeOH): δ 7.51 (1H, dd, J1 8.0 Hz, J2 1.6 Hz), δ 7.41 (1H, d, J 1.2 Hz), δ 7.32 (1H, d, J 8.0 Hz), δ 5.27 (1H, t, J 4.8 Hz), δ 5.09 (2H, dd, J1 50.0 Hz, J2 15.6 Hz), δ 3.68 (2H, t, J 5.6 Hz), δ 3.11 (3H, s), δ 3.02 (2H, t, J 4.0 Hz), δ 2.82 (2H, t, J 5.6 Hz).

Provenance & Evidence