N-Methylpropylamine → HCID 44481900, compound

HRID 452417Notes

Reaction equation

HRID 452417 reaction equation
Br[CH2:2][CH:3]1[O:8][C:7]2[CH:9]=[C:10]([S:13]([CH3:16])(=[O:15])=[O:14])[CH:11]=[CH:12][C:6]=2[CH2:5][O:4]1.[CH3:17][NH:18][CH2:19][CH2:20][CH3:21]>CCO>[CH3:17][N:18]([CH2:2][CH:3]1[O:8][C:7]2[CH:9]=[C:10]([S:13]([CH3:16])(=[O:15])=[O:14])[CH:11]=[CH:12][C:6]=2[CH2:5][O:4]1)[CH2:19][CH2:20][CH3:21]

Participants

4

Reactant 2

HCID 12315N-MethylpropylamineHCID 668864402-(bromomethyl)-7-(methylsulfonyl)-4H-1,3-benzodioxine

Product 1

HCID 44481900HCID 44481900, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Preparation according to Example 22 using 2-(bromomethyl)-7-(methylsulfonyl)-4H-1,3-benzodioxine (30 mg, 0.10 mmol), N-methylpropan-1-amine (0.50 ml, 4.9 mmol) and EtOH (1.0 ml). MS m/z (rel. intensity, 70 eV) 299 (M+, 1), 87 (6), 86 (bp), 77 (4), 58 (8).

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-4e8fc29d2de64c4180cb4422b09089fa
Source dataset
uspto-grants-2013_07
Patent number
US08492372B2

Reaction notes

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