HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylamine → N-{[5-Fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxin-2-YL]methyl}-2-methylpropan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylamine | HCID 6558 | — |
| Reactant | 2-(bromomethyl)-5-fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxine | HCID 66887621 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-{[5-Fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxin-2-YL]methyl}-2-methylpropan-1-amine | HCID 44482177 | — |
Reaction Steps
Preparation according to Example 34 using 2-(bromomethyl)-5-fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxine (7 mg, 0.021 mmol), 2-methylpropan-1-amine (0.5 ml) and EtOH (3 ml). MS m/z (rel. intensity, 70 eV) 317 (M+, 0.4), 274 (11), 141 (15), 86 (bp), 72 (29), 57 (14).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492372B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-4a446b95d7fe49f0b458435d5d4f63f2 |
| Source note | uspto-grants-2013_07 |