HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylpropylamine → N-{[5-Fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxin-2-YL]methyl}-N-methylpropan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylpropylamine | HCID 12315 | — |
| Reactant | 2-(bromomethyl)-5-fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxine | HCID 66887621 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-{[5-Fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxin-2-YL]methyl}-N-methylpropan-1-amine | HCID 44482448 | — |
Reaction Steps
Preparation according to Example 34 using 2-(bromomethyl)-5-fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxine (8.5 mg, 0.026 mmol), N-methylpropan-1-amine (0.50 ml) and EtOH (3 ml). MS m/z (rel. intensity, 70 eV) 317 (M+, 0.3), 95 (5), 87 (6), 86 (bp), 75 (5), 58 (15).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492372B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-f9692752df834227a157de73cb591f0f |
| Source note | uspto-grants-2013_07 |