HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-benzyl-3-oxopropanoate → 6-(4-benzyl-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)-N-[3-(benzyloxy)propyl]-N-cyclopentylpyridine-3-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-benzyl-3-oxopropanoate | HCID 15570304 | — |
| Reactant | N-[3-(benzyloxy)propyl]-N-cyclopentyl-6-hydrazinylpyridine-3-sulfonamide | HCID 67455278 | — |
| Product | 6-(4-benzyl-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)-N-[3-(benzyloxy)propyl]-N-cyclopentylpyridine-3-sulfonamide | HCID 67454886 | 55% |
Reaction Steps
According to the process described in Example 1.3, starting with 0.19 g of methyl 2-benzyl-3-oxopropanoate and 0.4 g of N-[3-(benzyloxy)propyl]-N-cyclopentyl-6-hydrazinylpyridine-3-sulfonamide, 0.29 g of 6-(4-benzyl-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)-N-[3-(benzyloxy)propyl]-N-cyclopentylpyridine-3-sulfonamide is obtained in the form of a beige-coloured solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08541455B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-7827f2a9f51e4049a8aa62430ec89f88 |
| Source note | uspto-grants-2013_09 |