HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 1,3-Benzothiazole-6-carbohydrazide trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Tert-butyl 2-(benzothiazol-6-ylcarbonyl)hydrazinecarboxylate | HCID 68663659 | — |
| Product | 1,3-Benzothiazole-6-carbohydrazide trifluoroacetate | HCID 68663855 | 94% |
Reaction Steps
A mixture of tert-butyl 2-(benzothiazol-6-ylcarbonyl)hydrazinecarboxylate (5.28 g, 18.0 mmol) and trifluoroacetic acid (20 mL) was stirred at room temperature for 1 hr. Trifluoroacetic acid was evaporated under reduced pressure, and the residue was recrystallized from ethanol to give the title compound (5.18 g, yield 94%) as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492378B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-d5fd8e9be6554006877e76044969f446 |
| Source note | uspto-grants-2013_07 |