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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 452616Generated: October 25, 2026

3-(3-Fluorophenyl)propionic acid → Tert-butyl [4-[[2-[3-(3-fluorophenyl)propanoyl]hydrazino]carbonyl]-2-pyridyl]carbamate

https://huagongshe.com/reaction/452616

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Fluorophenyl)propionic acidHCID 2737489—
ReactantTert-butyl [4-(hydrazinocarbonyl)-2-pyridyl]carbamateHCID 86640026—
ProductTert-butyl [4-[[2-[3-(3-fluorophenyl)propanoyl]hydrazino]carbonyl]-2-pyridyl]carbamateHCID 8664002560%

Reaction Steps

In the same manner as in Reference Example 1 and using 3-(3-fluorophenyl)propionic acid instead of benzothiazole-6-carboxylic acid and tert-butyl[4-(hydrazinocarbonyl)-2-pyridyl]carbamate instead of tert-butyl carbazate, the title compound (yield 60%) was obtained as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08492378B2
Source datasetuspto-grants-2013_07
ORD IDord-2c88286c69ad48efb8394d62cacbe8aa
Source noteuspto-grants-2013_07