HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Chloromethyl)cyclopropane → 2-[(Cyclopropylmethyl)thio]-5-(2,3-dihydro-1-benzofuran-5-yl)-1,3,4-oxadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Chloromethyl)cyclopropane | HCID 80013 | — |
| Reactant | HCID 178527934 | HCID 178527934 | — |
| Product | 2-[(Cyclopropylmethyl)thio]-5-(2,3-dihydro-1-benzofuran-5-yl)-1,3,4-oxadiazole | HCID 68662870 | 56% |
Reaction Steps
In the same manner as in Example 1 and using 5-(2,3-dihydro-1-benzofuran-5-yl)-1,3,4-oxadiazole-2-thiol instead of 5-(benzothiazol-6-yl)-1,3,4-oxadiazole-2-thiol and (chloromethyl)cyclopropane instead of 3-(trifluoromethyl)benzyl chloride, the title compound (yield 56%) was obtained as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492378B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-566de77f5da0477fa0b1c173cc9c35d2 |
| Source note | uspto-grants-2013_07 |