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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 452702Erstellt: 25. Oktober 2026

3-(3-Fluorophenyl)propionic acid → 2-(2,3-Dihydro-1-benzofuran-5-yl)-5-[2-(3-fluorophenyl)ethyl]-1,3,4-oxadiazole

https://huagongshe.com/reaction/452702

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-(3-Fluorophenyl)propionic acidHCID 2737489—
Edukt2,3-Dihydro-1-benzofuran-5-carbohydrazideHCID 18526469—
Produkt2-(2,3-Dihydro-1-benzofuran-5-yl)-5-[2-(3-fluorophenyl)ethyl]-1,3,4-oxadiazoleHCID 4459038059%

Reaktionsschritte

In the same manner as in Example 14 and using 2,3-dihydro-1-benzofuran-5-carbohydrazide instead of 1H-benzotriazole-5-carbohydrazide and 3-(3-fluorophenyl)propionic acid instead of 3-(3-cyanophenyl)propionic acid, the title compound (yield 59%) was obtained as colorless crystals.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08492378B2
Quelldatensatzuspto-grants-2013_07
ORD IDord-7071985ea8d54a5986ab828e97353e5d
Quellennotizuspto-grants-2013_07