HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(p-Methoxyphenyl)propionic acid → 2-(1-Benzofuran-5-yl)-5-[2-(4-methoxyphenyl)ethyl]-1,3,4-oxadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(p-Methoxyphenyl)propionic acid | HCID 95750 | — |
| Reactant | 1-Benzofuran-5-carbohydrazide | HCID 68664129 | — |
| Product | 2-(1-Benzofuran-5-yl)-5-[2-(4-methoxyphenyl)ethyl]-1,3,4-oxadiazole | HCID 68663955 | 53% |
Reaction Steps
In the same manner as in Example 14 and using 1-benzofuran-5-carbohydrazide instead of 1H-benzotriazole-5-carbohydrazide and 3-(4-methoxyphenyl)propionic acid instead of 3-(3-cyanophenyl)propionic acid, the title compound (yield 53%) was obtained as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492378B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-9f709825513e434b91d753863e799092 |
| Source note | uspto-grants-2013_07 |