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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 452718Generated: October 25, 2026

4-(4-Methoxyphenyl)butyric acid → 2-(1-Benzofuran-5-yl)-5-[3-(4-methoxyphenyl)propyl]-1,3,4-oxadiazole

https://huagongshe.com/reaction/452718

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Methoxyphenyl)butyric acidHCID 78280—
Reactant1-Benzofuran-5-carbohydrazideHCID 68664129—
Product2-(1-Benzofuran-5-yl)-5-[3-(4-methoxyphenyl)propyl]-1,3,4-oxadiazoleHCID 6866393315%

Reaction Steps

In the same manner as in Example 14 and using 1-benzofuran-5-carbohydrazide instead of 1H-benzotriazole-5-carbohydrazide and 4-(4-methoxyphenyl)butyric acid instead of 3-(3-cyanophenyl)propionic acid, the title compound (yield 15%) was obtained as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08492378B2
Source datasetuspto-grants-2013_07
ORD IDord-b0702f4bdb514d6dbdadc40c0726b340
Source noteuspto-grants-2013_07