m-Xylyl bromide → HCID 68663222, compound

HRID 452732Notes

Reaction equation

HRID 452732 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:13]3[CH:14]=[C:15]([C:18]4[O:22][C:21]([SH:23])=[N:20][N:19]=4)[CH:16]=[CH:17][C:12]=3[O:11][CH:10]=2)=[CH:5][CH:4]=1.[CH3:24][C:25]1[CH:26]=[C:27]([CH:30]=[CH:31][CH:32]=1)[CH2:28]Br>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[C:13]3[CH:14]=[C:15]([C:18]4[O:22][C:21]([S:23][CH2:24][C:25]5[CH:32]=[CH:31][CH:30]=[C:27]([CH3:28])[CH:26]=5)=[N:20][N:19]=4)[CH:16]=[CH:17][C:12]=3[O:11][CH:10]=2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 12099m-Xylyl bromideHCID 178488802HCID 178488802, compound

Product 1

HCID 68663222HCID 68663222, compoundYield 80%

Procedure

In the same manner as in Example 1 and using 5-[3-(4-methoxyphenyl)-1-benzofuran-5-yl]-1,3,4-oxadiazole-2-thiol instead of 5-(benzothiazol-6-yl)-1,3,4-oxadiazole-2-thiol and 3-methylbenzyl bromide instead of 3-(trifluoromethyl)benzyl chloride, the title compound (yield 80%) was obtained as colorless crystals.

Sources & evidence

ORD record
ord-857b9ae8e32842fd963478363c2a1ac3
Source dataset
uspto-grants-2013_07
Patent number
US08492378B2

Reaction notes

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