Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Fluoro-4-methoxybenzyl chloride → 2-[(3-Fluoro-4-methoxybenzyl)thio]-5-[3-(4-methoxyphenyl)-1-benzofuran-5-yl]-1,3,4-oxadiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Fluoro-4-methoxybenzyl chloride | HCID 2060903 | — |
| 반응물 | HCID 178488802 | HCID 178488802 | — |
| 생성물 | 2-[(3-Fluoro-4-methoxybenzyl)thio]-5-[3-(4-methoxyphenyl)-1-benzofuran-5-yl]-1,3,4-oxadiazole | HCID 68664135 | 86% |
반응 단계
In the same manner as in Example 1 and using 5-[3-(4-methoxyphenyl)-1-benzofuran-5-yl]-1,3,4-oxadiazole-2-thiol instead of 5-(benzothiazol-6-yl)-1,3,4-oxadiazole-2-thiol and 3-fluoro-4-methoxybenzyl chloride instead of 3-(trifluoromethyl)benzyl chloride, the title compound (yield 86%) was obtained as colorless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08492378B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-22f058710d9d43b3937f38904ba34b86 |
| 출처 메모 | uspto-grants-2013_07 |