HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methylthio)-3-(trifluoromethyl)benzyl chloride → 2-(2,3-Dihydro-1-benzofuran-5-yl)-5-[[4-(methylthio)-3-(trifluoromethyl)benzyl]thio]-1,3,4-oxadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methylthio)-3-(trifluoromethyl)benzyl chloride | HCID 68663128 | — |
| Reactant | HCID 178527934 | HCID 178527934 | — |
| Product | 2-(2,3-Dihydro-1-benzofuran-5-yl)-5-[[4-(methylthio)-3-(trifluoromethyl)benzyl]thio]-1,3,4-oxadiazole | HCID 68663110 | 89% |
Reaction Steps
In the same manner as in Example 7 and using 5-(2,3-dihydro-1-benzofuran-5-yl)-1,3,4-oxadiazole-2-thiol instead of 5-(1H-indazol-5-yl)-1,3,4-oxadiazole-2-thiol and 4-(methylthio)-3-(trifluoromethyl)benzyl chloride instead of 3-(trifluoromethyl)benzyl chloride, the title compound (yield 89%) was obtained as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492378B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-b16ee4ce8753438c8e716bf930a5db98 |
| Source note | uspto-grants-2013_07 |