Ethyl orthopropionate → HCID 68664252, compound

HRID 452797Notes

Reaction equation

[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:13]3[CH:14]=[C:15]([C:18]([NH:20][NH2:21])=[O:19])[CH:16]=[CH:17][C:12]=3[O:11][CH:10]=2)=[CH:5][CH:4]=1.[C:22](OCC)(OCC)(OCC)[CH2:23][CH3:24]>>[CH2:23]([C:24]1[O:19][C:18]([C:15]2[CH:16]=[CH:17][C:12]3[O:11][CH:10]=[C:9]([C:6]4[CH:5]=[CH:4][C:3]([S:2][CH3:1])=[CH:8][CH:7]=4)[C:13]=3[CH:14]=2)=[N:20][N:21]=1)[CH3:22]

Participants

Reactant 2

HCID 66995Ethyl orthopropionate

HCID 44480698HCID 44480698, compound

Product 1

HCID 68664252HCID 68664252, compoundYield 9%

Procedure

In the same manner as in Example 239 and using 3-[4-(methylthio)phenyl]-1-benzofuran-5-carbohydrazide instead of 2-[[4-(methylthio)phenyl]amino]isonicotinohydrazide and using triethyl orthopropionate instead of triethyl orthoacetate, the title compound (yield 9%) was obtained as colorless crystals.

Sources & evidence

ORD record: ord-8d12e75418bb477d913f2342dc3a7be3
Source dataset: uspto-grants-2013_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08492378B2

Reaction notes

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