HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine tetrahydrofuran → HCID 68663531, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine tetrahydrofuran | HCID 66615946 | — |
| Reactant | 2-(Methylsulfonyl)-5-[3-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-yl]-1,3,4-oxadiazole | HCID 68664360 | — |
| Product | HCID 68663531 | HCID 68663531 | 33% |
Reaction Steps
In the same manner as in Example 110 and using 2-(methylsulfonyl)-5-[3-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-yl]-1,3,4-oxadiazole instead of 2-(2,3-dihydro-1-benzofuran-5-yl)-5-(methylsulfonyl)-1,3,4-oxadiazole and using 2M methylamine-tetrahydrofuran solution instead of 3-fluorobenzylalcohol, the title compound (yield 33%) was obtained as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492378B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-3fec2eea3dd24afeb1a299c480b922e6 |
| Source note | uspto-grants-2013_07 |