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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 452831Generated: October 30, 2026

2-Chlorophenylboronic acid → 3-(2-Chlorophenyl)-5-(5-methyl-1,3,4-oxadiazol-2-yl)furo[3,2-b]pyridine

https://huagongshe.com/reaction/452831

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chlorophenylboronic acidHCID 2734322—
Reactant3-Bromo-5-(5-methyl-1,3,4-oxadiazol-2-yl)furo[3,2-b]pyridineHCID 68663099—
Product3-(2-Chlorophenyl)-5-(5-methyl-1,3,4-oxadiazol-2-yl)furo[3,2-b]pyridineHCID 686636466%

Reaction Steps

In the same manner as in Example 132 and using 3-bromo-5-(5-methyl-1,3,4-oxadiazol-2-yl)furo[3,2-b]pyridine instead of 2-(3-bromo-1-benzofuran-5-yl)-5-methyl-1,3,4-oxadiazole, using (2-chlorophenyl)boronic acid instead of (4-fluorophenyl)boronic acid, and using [1,1′-bis(diphenylphosphino)ferrocene]palladium(II) chloride dichloromethane complex instead of tetrakis(triphenylphosphine)palladium(0), the title compound (yield 6%) was obtained as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08492378B2
Source datasetuspto-grants-2013_07
ORD IDord-ee1fbb1f428e409ebd39ec68a7fefb5e
Source noteuspto-grants-2013_07