Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 45300Generated: October 26, 2026

Metformin Hydrochloride → HCID 178476642, compound

https://huagongshe.com/reaction/45300

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMetformin HydrochlorideHCID 14219—
ReactantSodium Acetate TrihydrateHCID 23665404—
SolventWaterHCID 962—
ProductHCID 178476642HCID 17847664251.6%

Reaction Steps

20.0 g (1 equivalent) of metformin hydrochloride, 50 Ml of water, and 19.72 g (1.2 equivalents) of sodium acetate trihydrate were added to a reactor, and stirred. Then the resulting crystal was filtered and washed with acetone, and then dried at 60° C. to obtain 11.72 g of metformin acetate (yield: 51.3%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08541474B2
Source datasetuspto-grants-2013_09
ORD IDord-8f6f02ec54e8446e91f4b5525381d122
Source noteuspto-grants-2013_09