HuagongsheHuagongshe Chemistry Print Report · For research reference only
Metformin Hydrochloride → HCID 178476642, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Metformin Hydrochloride | HCID 14219 | — |
| Reactant | Sodium Acetate Trihydrate | HCID 23665404 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178476642 | HCID 178476642 | 51.6% |
Reaction Steps
20.0 g (1 equivalent) of metformin hydrochloride, 50 Ml of water, and 19.72 g (1.2 equivalents) of sodium acetate trihydrate were added to a reactor, and stirred. Then the resulting crystal was filtered and washed with acetone, and then dried at 60° C. to obtain 11.72 g of metformin acetate (yield: 51.3%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08541474B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-8f6f02ec54e8446e91f4b5525381d122 |
| Source note | uspto-grants-2013_09 |