2,4-Dichlorobenzoyl chloride → HCID 59369695, compound

Participants

Reaction Steps

Following the procedure as described in Example 2, making variations only as required to use 2,4-dichlorobenzoyl chloride in place of benzoyl chloride to react with 2-amino-4-methylthiazole-5-carboxylic acid benzylamide, the title compound was obtained as a white solid in 21% yield; 1H NMR (CDCl3, 300 MHz) δ 7.74 (d, J=8.3 Hz, 1H), 7.45-7.24 (m, 7H), 5.99 (s, 1H), 4.57 (d, J=5.4 Hz, 2H), 2.35 (s, 3H); MS (ES+) m/z 420.0 (M+1).

Provenance & Evidence