HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(tert-Butyl)-4-(piperazin-1-yl)-6-(trifluoromethyl)pyrimidine → 2-{4-[4-(2-tert-Butyl-6-trifluoromethyl-pyrimidin-4-yl)-piperazin-1-yl]-butyl}-6-methyl-2H-[1,2,4]triazine-3,5-dione hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(tert-Butyl)-4-(piperazin-1-yl)-6-(trifluoromethyl)pyrimidine | HCID 18399610 | — |
| Reactant | 2-(4-Chloro-butyl)-6-methyl-2H-[1,2,4]triazine-3,5-dione | HCID 59614492 | — |
| Product | 2-{4-[4-(2-tert-Butyl-6-trifluoromethyl-pyrimidin-4-yl)-piperazin-1-yl]-butyl}-6-methyl-2H-[1,2,4]triazine-3,5-dione hydrochloride | HCID 42603342 | — |
Reaction Steps
2-{4-[4-(2-tert-Butyl-6-trifluoromethyl-pyrimidin-4-yl)-piperazin-1-yl]-butyl}-6-methyl-2H-[1,2,4]triazine-3,5-dione hydrochloride was prepared from 2-(4-chloro-butyl)-6-methyl-2H-[1,2,4]triazine-3,5-dione and 2-tert-butyl-4-piperazin-1-yl-6-trifluoromethyl-pyrimidine by analogy to the process described in example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492540B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-17d582121b2b464a8eee993d8e1c038d |
| Source note | uspto-grants-2013_07 |