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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 453749Generated: October 29, 2026

HCID 66726836, compound → HCID 25174838, compound

https://huagongshe.com/reaction/453749

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66726836HCID 66726836—
SolventTetrahydrofuranHCID 8028—
ProductHCID 25174838HCID 2517483853.7%

Reaction Steps

(R)-2,3-Dihydrobenzo[1,4]dioxin-2-yl-[(S*)-3-(3-trifluoromethylphenyl)piperidin-1-yl]methanone (29 mg, 0.074 mmol) was treated with BH3 THF according to the above general procedure. Flash chromatography gave 15 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08492549B2
Source datasetuspto-grants-2013_07
ORD IDord-4afe93a075d649c08e55dc951497e00c
Source noteuspto-grants-2013_07