HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Hydroxyquinoline → HCID 22030868, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Hydroxyquinoline | HCID 11374 | — |
| Reactant | 4-Chloro-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazoline | HCID 11782230 | — |
| Product | HCID 22030868 | HCID 22030868 | 94% |
Reaction Steps
Using a procedure analogous to that described for Example 10, 4-chloro-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazoline (74 mg, 0.23 mmol), (prepared as described for the starting material in Example 10), was reacted with 6-hydroxyquinoline (41 mg, 0.28 mol) to give 6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)-4-(quinolin-6-yloxy)quinazoline (89 mg, 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492560B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-bba66ec8f7aa4e54b4459348c35f14ba |
| Source note | uspto-grants-2013_07 |