2-methyl-1H-indol-5-ol → 7-Benzyloxy-6-methoxy-4-(2-methylindol-5-yloxy)quinazoline

Participants

Reaction Steps

Using an analogous procedure to that described in Example 32, 7-benzyloxy-4-chloro-6-methoxyquinazoline (1 g, 3.33 mmol), (prepared as described for the starting material in Example 1), was reacted with 5-hydroxy-2-methylindole (0.59 g, 4 mmol) to give 7-benzyloxy-6-methoxy-4-(2-methylindol-5-yloxy)quinazoline (1.25 g, 91%).

Provenance & Evidence