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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 454093Generated: October 30, 2026

Diethylene Glycol Monomethyl Ether → HCID 22030570, compound

https://huagongshe.com/reaction/454093

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethylene Glycol Monomethyl EtherHCID 8134—
Reactant7-hydroxy-4-(1H-indol-5-yloxy)-6-methoxyquinazolineHCID 135763116—
ProductHCID 22030570HCID 2203057042.2%

Reaction Steps

Using an analogous procedure to that described in Example 91, 7-hydroxy-4-(indol-5-yloxy)-6-methoxyquinazoline (89 mg) was reacted with 2-(2-methoxyethoxy)ethanol (70 mg) to give 4-(indol-5-yloxy)-6-methoxy-7-(2-(2-methoxyethoxy)ethoxy)quinazoline (50 mg, 42%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08492560B2
Source datasetuspto-grants-2013_07
ORD IDord-4ec5caa53d15428788adb5a814b6418b
Source noteuspto-grants-2013_07