HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Benzyloxy-6-methoxyindole → 6-Methoxy-1H-indol-5-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Benzyloxy-6-methoxyindole | HCID 260800 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-Methoxy-1H-indol-5-ol | HCID 164957 | 87% |
Reaction Steps
5-Benzyloxy-6-methoxyindole (253 mg, 1.0 mmol) was hydrogenated at 1 atmosphere pressure in methanol (10 ml) with 10% palladium on carbon (50 mg) for 2 hours at 25° C. The catalyst was filtered off and the filtrate evaporated to give 5-hydroxy-6-methoxylindole (141 mg, 87%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492560B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-6dfaa82a21cc4575987b571cae707983 |
| Source note | uspto-grants-2013_07 |