Potassium Carbonate → HCID 58508626, compound

Participants

Reaction Steps

Potassium carbonate (0.12 g) was added to a solution mixture of the obtained tert-butyl 2-(2-acetoxy-4-chlorobenzamido)-4-phenylbenzoate (0.13 g) in methanol (2.5 mL) and dioxane (2.5 mL), followed by stirring at room temperature for 2 hours. The solvent was evaporated under reduced pressure, and a 10% aqueous solution of citric acid and ethyl acetate were added to the residue. The organic layer was separated, washed with a saturated aqueous solution of sodium chloride, and dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure to obtain 0.11 of tert-butyl 2-(4-chloro-2-hydroxybenzamido)-4-phenylbenzoate as a white solid.

Provenance & Evidence