Trifluoroacetic acid → HCID 58508569, compound

Participants

Reaction Steps

A trifluoroacetic acid (4 mL) solution of the obtained tert-butyl 2-(7-hydroxy-2,3-dihydrobenzo[1,4]dioxine-6-carboxamido)-4-phenylbenzoate (0.37 g) was stirred at room temperature for 15 minutes. Methylene chloride (10 mL) was added to the reaction mixture, followed by stirring at room temperature for 1 hour and 15 minutes. The solvent was evaporated under reduced pressure, and ethyl acetate was added to the obtained residue. The solid substance was collected by filtration to obtain 0.30 g of 2-(7-hydroxy-2,3-dihydrobenzo[1,4]dioxine-6-carboxamido)-4-phenylbenzoic acid as a white solid.

Provenance & Evidence