HCID 58508729, compound → HCID 46853604, compound

Participants

Reaction Steps

A solution mixture of the obtained tert-butyl 2-(2-hydroxy-5-(pyrimidin-5-yl)benzamido)-4-phenylbenzoate (0.73 g) in methylene chloride (25 mL) and trifluoroacetic acid (10 mL) was stirred at room temperature overnight. The solvent was evaporated under reduced pressure, and water was added to the obtained residue. After adjusting the pH to 6.5 with a saturated aqueous solution of sodium bicarbonate, the solid substance was collected by filtration to obtain 0.49 g of 2-(2-hydroxy-5-(pyrimidin-5-yl)benzamido)-4-phenylbenzoic acid as a white solid.

Provenance & Evidence