HCID 136198174, compound → HCID 135873928, compound

Participants

Reaction Steps

A solution mixture of the obtained tert-butyl 2-(2-hydroxy-5-(pyrimidin-2-yl)benzamido)-4-phenylbenzoate (5 mg) in methylene chloride (2 mL) and trifluoroacetic acid (0.50 mL) was stirred at room temperature for 3 hours and 30 minutes. The solvent was evaporated under reduced pressure, and water and chloroform were added to the residue. The organic layer was separated and dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure. Diisopropyl ether was added to the obtained residue, and the solid substance was collected by filtration to obtain 4 mg of 2-(2-hydroxy-5-(pyrimidin-2-yl)benzamido)-4-phenylbenzoic acid as a white solid.

Provenance & Evidence