HCID 66990969, compound → HCID 136198172, compound

Participants

Reaction Steps

To a solution mixture of the obtained tert-butyl 2-(2-(benzyloxy)-5-(1,3,4-oxadiazol-2-yl)benzamido)-4-phenylbenzoate (0.049 g) in ethyl acetate (1 mL) and methanol (1 mL), 10% palladium-carbon (25 mg) was added, followed by stirring under a hydrogen atmosphere at room temperature for 2 hours. Ethyl acetate was added to the reaction mixture, and the insoluble substance was removed by filtration. The solvent was evaporated under reduced pressure, and diisopropyl ether was added to the obtained residue. The solid substance was collected by filtration to obtain 0.034 g of tert-butyl 2-(2-hydroxy-5-(1,3,4-oxadiazol-2-yl)benzamido)-4-phenylbenzoate as a white solid.

Provenance & Evidence