Citric Acid → HCID 58508945, compound

Participants

Reaction Conditions

Reaction Steps

Dioxane (5.0 mL) and a 4 mol/L aqueous solution of sodium hydroxide (0.31 mL) were added to the obtained methyl 2-(2-acetoxy-5-(pyridin-3-yl)benzamido)-4-(furan-3-yl)benzoate (0.11 g), followed by stirring at 50 to 55° C. for 1 hours. The reaction mixture was cooled to room temperature, and a 10% aqueous solution of citric acid (6 mL) was added thereto. The solid substance was collected by filtration to obtain 0.081 g of 4-(furan-3-yl)-2-(2-hydroxy-5-(pyridin-3-yl)benzamido)-benzoic acid as a yellow solid.

Provenance & Evidence