Acetone → HCID 66990532, compound

Participants

Reaction Steps

Potassium carbonate (1.6 g) was added to a solution mixture of methyl 2-(5-acetoxy-2-(benzyloxy)benzamido)-4-phenylbenzoate (3.8 g) in chloroform (5.0 mL), methanol (10 mL), and acetone (10 mL), followed by stirring at room temperature for 1 hour. The insoluble substance was removed by filtration, and then the solvent was evaporated under reduced pressure, and 1.0 mol/L hydrochloric acid and chloroform were added to the residue. The organic layer was separated, washed with a saturated aqueous solution of sodium chloride, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to obtain 3.4 g of methyl 2-(2-(benzyloxy)-5-hydroxybenzamido)-4-phenylbenzoate as a white solid.

Provenance & Evidence