Water → HCID 86659239, compound

Participants

Reaction Steps

Water (1.0 mL), methanesulfonic acid (0.029 mL), and activated carbon (0.020 g) were added to a solution mixture of the obtained 2-(2-hydroxy-5-(2-(4-methylpiperazin-1-yl)ethoxy)benzamido)-4-phenylbenzoic acid (0.10 g) in tetrahydrofuran (2.0 mL) and ethanol (1.0 mL), followed by stirring at room temperature for 30 minutes. The insoluble substance was removed by filtration, and then the solvent was evaporated under reduced pressure. Acetone was added to the obtained residue, and the solid substance was collected by filtration to obtain 0.095 g of 2-(2-hydroxy-5-(2-(4-methylpiperazin-1-yl)ethoxy)benzamido)-4-phenylbenzoic acid dimethanesulfonate as a white solid.

Provenance & Evidence