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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 4547Generated: October 28, 2026

1-(2,3-Epoxypropoxy)-4-(2-methoxyethoxy)benzene → 1-[N-[2-(3-carbamoyl-2-hydroxyphenoxy)ethyl]benzylamino]-3-[4-(2-methoxyethoxy)-phenoxy]propan-2-ol

https://huagongshe.com/reaction/4547

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2,3-Epoxypropoxy)-4-(2-methoxyethoxy)benzeneHCID 12621549—
Reactant3-(2-Benzylaminoethoxy)salicylamideHCID 20151303—
Product1-[N-[2-(3-carbamoyl-2-hydroxyphenoxy)ethyl]benzylamino]-3-[4-(2-methoxyethoxy)-phenoxy]propan-2-olHCID 54392941—

Reaction Steps

By reacting 2.5 g of 1-(2,3-epoxypropoxy)-4-(2-methoxyethoxy)benzene with 2.9 g of crude 3-(2-benzylaminoethoxy)salicylamide obtained according to Example (25c), analogously to Example (4a), 1-[N-[2-(3-carbamoyl-2-hydroxyphenoxy)ethyl]benzylamino]-3-[4-(2-methoxyethoxy)phenoxy]propan-2-ol is obtained as an oil which is further processed in this state

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04727067
Source datasetuspto-grants-1988_02
ORD IDord-4138b5976c30454da791ce9f725bb448
Source noteuspto-grants-1988_02