Trifluoroacetic acid → HCID 58508858, compound

Participants

Reaction Steps

Trifluoroacetic acid (2.0 mL) was added to the obtained tert-butyl 4-(furan-2-yl)-2-(2-hydroxy-5-(morpholin-4-yl)benzamido)benzoate (0.085 g), followed by stirring at room temperature for 30 minutes. The solvent was evaporated under reduced pressure, and water and 2-propanol were added to the residue. After adjusting the pH to 6.0 with a saturated aqueous solution of sodium bicarbonate, the solid substance was collected by filtration to obtain 0.064 g of 4-(furan-2-yl)-2-(2-hydroxy-5-(morpholin-4-yl)benzamido)benzoic acid as a yellow solid.

Provenance & Evidence