Hydrochloric Acid → HCID 58508916, compound

Participants

Reaction Conditions

Reaction Steps

A 2.0 mol/L aqueous solution of sodium hydroxide (0.27 mL) was added to a methanol (1.0 mL) suspension of the obtained methyl 2-(2-hydroxy-5-(1-methylpiperidin-4-yl)benzamido)-4-(3-methoxyphenyl)benzoate (0.026 g), followed by stirring at 50° C. for 3 hours. After cooling the reaction mixture to room temperature and adjusting the pH to 6.0 with 2.0 mol/L hydrochloric acid, the solid substance was collected by filtration to obtain 0.025 g of 2-(2-hydroxy-5-(1-methylpiperidin-4-yl)benzamido)-4-(3-methoxyphenyl)benzoic acid as a light yellow solid.

Provenance & Evidence