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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 454735Generated: October 30, 2026

Trifluoroacetic acid → HCID 58508458, compound

https://huagongshe.com/reaction/454735

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 58508444HCID 58508444—
ProductHCID 58508458HCID 5850845889.3%

Reaction Steps

Trifluoroacetic acid (5 mL) was added to the obtained tert-butyl 2-(5-phenylpyridine-3-carboxamido)-4-(1H-pyrazol-1-yl)benzoate (68 mg), followed by stirring at room temperature for 4 hours. The solvent was evaporated under reduced pressure, and methanol was added to the obtained residue. The solid substance was collected by filtration to obtain 53 mg of 2-(5-phenylpyridine-3-carboxamido)-4-(1H-pyrazol-1-yl)benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08492582B2
Source datasetuspto-grants-2013_07
ORD IDord-adf6e0247a8341d2a6c66223884b72f3
Source noteuspto-grants-2013_07