Trifluoroacetic acid → HCID 66990611, compound

Participants

Reaction Steps

Trifluoroacetic acid (7.9 mL) was added to the obtained 4-(2-((tert-butoxycarbonyl)(ethyl)amino)phenyl)-2-(5-phenylpyridine-3-carboxamido)benzoic acid (0.79 g), followed by stirring at room temperature for 1 hour. The solvent was evaporated under reduced pressure, and a 30% aqueous solution of ethanol was added to the obtained residue. After adjusting the pH to 5.0 with a 4.0 mol/L aqueous solution of sodium hydroxide, the solid substance was collected by filtration to obtain 0.61 g of 4-(2-(ethylamino)phenyl)-2-(5-phenylpyridine-3-carboxamido)benzoic acid as a yellow solid.

Provenance & Evidence