Trifluoroacetic acid → HCID 58508716, compound

Participants

Reaction Steps

Trifluoroacetic acid (5 mL) was added to the obtained tert-butyl 4-phenyl-2-(6-(pyridin-4-yl)pyridine-3-carboxamido)benzoate (25 mg), followed by stirring at room temperature for 3 hours. The solvent was evaporated under reduced pressure, and water was added to the obtained residue. After adjusting the pH to 5.5 with a saturated aqueous solution of sodium bicarbonate, the solid substance was collected by filtration to obtain 20 mg of 4-phenyl-2-(6-(pyridin-4-yl)pyridine-3-carboxamido)benzoic acid as a yellow solid.

Provenance & Evidence