HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylparaben → HCID 57615137, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylparaben | HCID 8434 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(Chloroethoxy)ethanol | HCID 12361 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 57615137 | HCID 57615137 | 56% |
Reaction Steps
2-(2-Chloroethoxy)ethanol (1, 0.18 mol), ethyl 4-hydroxybenzoate (2, 0.12 mol) and potassium carbonate (0.24 mol) were stirred in N,N-dimethylformamide (DMF) at 120° C. for 10 hours to obtain ethyl 4-(2-(2-hydroxyethoxy)-ethoxy)benzoate 3, followed by tosylation according to usual process to obtain a compound 4 in a yield of 56%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08496848B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-284a9e055e564dbbbc9ec1a4eb78c812 |
| Source note | uspto-grants-2013_07 |