HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Sulfate → HCID 58238575, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Sulfate | HCID 24436 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | (2,6-Diisopropylphenyl)[1-(2'-methoxybiphenyl-3-yl)ethylidene]amine | HCID 58238573 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 58238575 | HCID 58238575 | — |
Reaction Steps
To a suspension of 0.70 g (18.4 mmol) of LiAlH4 in 60 mL of THF, 2.25 g (5.84 mmol) of 39 was added. This reaction mixture was refluxed for 2 hr, and then saturated aqueous Na2SO4 was added. The organic layer was separated, and the aqueous layer was extracted with 2×50 mL of diethyl ether. The combined organic extract was evaporated to dryness, and the product was isolated by flash chromatography on silica gel 60 (40-63 um, eluent: hexanes-diethyl ether from 100:1 to 20:1, vol.) to yield 1.45 g (64%) of Fl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08541522B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-9aa044796f2a4b589cf199da4ec90909 |
| Source note | uspto-grants-2013_09 |