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HRID45498

反应详情

EQUATION

反应方程式

HRID 45498 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2cn[nH]c2)OC1(C)C
HCID2774010

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

C9H15BN2O2

结构：Clc1ccc(C2(c3ccc(Br)cc3)CCNCC2)cc1
HCID49760777

4-(4-Bromophenyl)-4-(4-chlorophenyl)piperidine

C17H17BrClN

PRODUCTS

生成物

1
结构：Clc1ccc(C2(c3ccc(-c4cn[nH]c4)cc3)CCNCC2)cc1
HCID11175137

AT7867

C20H20ClN3

PROCEDURE

实验过程

4-(4-Bromo-phenyl)-4-(4-chloro-phenyl)-piperidine was reacted with 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole following the procedure set out in Example 1 to give the title compound. LC/MS: (PS-A3) Rt 7.22 [M+H]+ 338.08. 1H NMR (Me-d3-OD) δ 2.64-2.74 (4H, m), 3.22-3.25 (4H, m), 7.33-7.45 (6H, m), 7.65 (2H, d), 8.37 (2H, s).