HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67073791, compound → HCID 66513497, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67073791 | HCID 67073791 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethylacetate methanol | HCID 21584119 | — |
| Product | HCID 66513497 | HCID 66513497 | 100% |
Reaction Steps
A mixture of [(R)-1-(4-Benzyloxy-2-methoxy-phenyl)-2-hydroxy-ethyl]-carbamic acid benzyl ester (1.2 g, 2.96 mmol) and Pd/C (120 mg) in MeOH/EtOAc (5:1, 10 mL) was stirred under H2 (1 atm) for overnight. The mixture was filtered and the filtrate was concentrated to give the titled compound (542 mg, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08497271B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-97eddcb5770e4aae98520da6377e8ae5 |
| Source note | uspto-grants-2013_07 |