反应详情

The title compound was prepared according to Method A and the experimentals described for compound 1 from 6-chloro-3-(chloromethyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridine hydrochloride and ethyl 1H-imidazole-2-carboxylate. m/e+ 416 for C20H17Cl2N4O2 [M+H]+; 1H-NMR (300 MHz, CDCl3) δ 8.04 (dd, J=0.9, 6.3 Hz, 1H), 7.60 (m, 3H), 7.42 (dd, J=6.3, 8.1 Hz, 2H), 7.27 (m, 1H), 7.11 (m, 1H), 6.67 (dd, J=2.1, 3.3 Hz, 1H), 6.07 (d, J=2.1 Hz, 2H), 4.48 (q, J=7.2 Hz, 2H), 1.48 (t, J=7.2 Hz, 3H) ppm; 13C-NMR (75 MHz, CDCl3, δ) 160.222, 135.309, 130.815, 130.735, 129.653, 129.593, 127.897, 123.336, 123.283, 122.261, 121.647, 121.573, 118.475, 62.384, 53.016, 41.598, 41.544, 14.534 ppm.