3-((1H-imidazol-1-yl)methyl)-6-methyl-2-p-tolylimidazo[1,2-a]pyridine → HCID 67028977, compound

HRID 455036Notes

Reaction equation

HRID 455036 reaction equation
[N:1]1([CH2:6][C:7]2[N:11]3[CH:12]=[C:13](C)[CH:14]=[CH:15][C:10]3=[N:9][C:8]=2[C:17]2[CH:22]=[CH:21][C:20](C)=[CH:19][CH:18]=2)C=[CH:4][N:3]=[CH:2]1.[ClH:24].ClCC1N2N=CC=CC2=[N:29]C=1C1C=CC(Cl)=CC=1.N1C=CN=N1>>[N:1]1([CH2:6][C:7]2[N:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]3=[N:9][C:8]=2[C:17]2[CH:22]=[CH:21][C:20]([Cl:24])=[CH:19][CH:18]=2)[CH:2]=[N:3][CH:4]=[N:29]1

Participants

4

Reactant 3

HCID 583370713-((1H-imidazol-1-yl)methyl)-6-methyl-2-p-tolylimidazo[1,2-a]pyridineHCID 67028922HCID 67028922, compoundHCID 178418936HCID 178418936, compound

Product 1

HCID 67028977HCID 67028977, compound

Procedure

The title compound was prepared according to Method A and the experimentals described for compound 1 from 3-(chloromethyl)-2-(4-chlorophenyl)imidazo[1,2-b]pyridazine hydrochloride and 1H-1,2,3-triazole. 1H-NMR (400 MHz, CDCl3, δ) 8.17 (d, J=6.8 Hz, 1H), 8.00 (s, 1H), 7.68 (m, 3H), 7.52 (m, 2H), 7.33 (m, 1H), 7.26 (m, 1H), 6.93 (m, 1H), 5.74 (s, 2H) ppm; m/e 310.

Sources & evidence

ORD record
ord-45bcc9d4100a4208a247edddcc27b45e
Source dataset
uspto-grants-2013_07
Patent number
US08497278B2

Reaction notes

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