Dimethylamine → 2-(6-Methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-ylmethyl)-2H-[1,2,4]triazole-3-carboxylic acid dimethylamide

Participants

Reaction Steps

The title compound was prepared according to the procedure described for compound 68 from methyl 1-((6-methyl-2-p-tolylimidazo[1,2-a]pyridin-3-yl)methyl)-1H-1,2,4-triazole-5-carboxylate and dimethylamine. m/e 375 for C21H23N6O [M+H]+; 1H-NMR (300 MHz, CDCl3) δ 8.35 (s, 2H), 7.87 (d, J=2.1 Hz, 1H), 7.72 (d, J=7.8 Hz, 2H), 7.54 (d, J=9.0 Hz, 1H), 7.26 (d, J=7.8 Hz, 2H), 7.10 (d, J=9.0 Hz, 1H), 6.00 (s, 1H), 3.06 (s, 3H), 3.00 (s, 3H), 2.40 (s, 3H), 2.35 (s, 3H) ppm; 13C-NMR (75 MHz, CDCl3, δ) 158.440, 150.213, 147.869, 146.313, 144.771, 138.154, 131.236, 131.236, 129.600, 128.812, 128.725, 122.609, 116.939, 113.480, 43.481, 38.888, 35.781, 21.585, 18.727 ppm.

Provenance & Evidence