Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → Bis(4-chlorophenyl)acetaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 4-Chloro-beta-(4-chlorophenyl)benzeneethanol | HCID 17533 | — |
| 반응물 | Triacetoxyperiodinane | HCID 159087 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Bis(4-chlorophenyl)acetaldehyde | HCID 167694 | — |
반응 단계
Dess-Martin periodinane (3.17 g, 7.49 mmol) was added to a solution of 2,2-Bis-(4-chloro-phenyl)-ethanol in dichloromethane (40 ml). The reaction mixture was stirred at room temperature for 17 hours under nitrogen, 2N NaOH added (15 ml) and the organic layer was separated, dried (MgSO4), filtered and concentrated to afford the title compounds which was used in the next step without further purification. LC/MS: (PS-B3) Rt 3.62 [M+H]+ 262.91.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541461B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-d4442f20d279450994c2700b8331657f |
| 출처 메모 | uspto-grants-2013_09 |