Ammonia → HCID 67029107, compound

HRID 455046Notes

Reaction equation

HRID 455046 reaction equation
C[NH:2]C(C1N(CC2N3C=C(C)C=CC3=NC=2C2C=CC(C)=CC=2)N=CN=1)=O.[F:28][C:29]1[CH:30]=[CH:31][C:32]2[N:33]([C:35]([CH2:45][N:46]3[CH:50]=[N:49][C:48]([C:51]([O:53]C)=O)=[N:47]3)=[C:36]([C:38]3[CH:43]=[CH:42][C:41]([F:44])=[CH:40][CH:39]=3)[N:37]=2)[CH:34]=1.N>>[F:28][C:29]1[CH:30]=[CH:31][C:32]2[N:33]([C:35]([CH2:45][N:46]3[CH:50]=[N:49][C:48]([C:51]([NH2:2])=[O:53])=[N:47]3)=[C:36]([C:38]3[CH:39]=[CH:40][C:41]([F:44])=[CH:42][CH:43]=3)[N:37]=2)[CH:34]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 670274852-(6-Methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-ylmethyl)-2H-[1,2,4]triazole-3-carboxylic acid methylamideHCID 67028671HCID 67028671, compound

Product 1

HCID 67029107HCID 67029107, compound

Procedure

The title compound was prepared according to the procedure described for compound 68 from methyl 1-((6-fluoro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-1H-1,2,4-triazole-3-carboxylate and ammonia. m/e+ 355 for C17H13F2N6O (M+H)+.

Sources & evidence

ORD record
ord-d57d7edc42034b6a85606dbcf347fd46
Source dataset
uspto-grants-2013_07
Patent number
US08497278B2

Reaction notes

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