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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 455048Generated: October 30, 2026

Methylamine → 1-((6-fluoro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-N-methyl-1H-1,2,4-triazole-5-carboxamide

https://huagongshe.com/reaction/455048

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant2-(6-Methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-ylmethyl)-2H-[1,2,4]triazole-3-carboxylic acid methylamideHCID 67027485—
ReactantMethyl 1-((6-fluoro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-1H-1,2,4-triazole-5-carboxylateHCID 67028848—
Product1-((6-fluoro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-N-methyl-1H-1,2,4-triazole-5-carboxamideHCID 67029106—

Reaction Steps

The title compound was prepared according to the procedure described for compound 68 from methyl 1-((6-fluoro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-1H-1,2,4-triazole-5-carboxylate and methylamine. m/e+ 368 for C18H15F2N6O (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08497278B2
Source datasetuspto-grants-2013_07
ORD IDord-dfd50c41a37846c3b55ce8ec2bce69d7
Source noteuspto-grants-2013_07