2-Mercaptopyrimidine → 1-(6-Methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-ylmethyl)-1H-pyrimidine-2-thione

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Reaction Steps

The title compound was prepared according to Method B and the experimentals described for compound 91 from 3-(chloromethyl)-6-methyl-2-p-tolylimidazo[1,2-a]pyridine hydrochloride and pyrimidine-2(1H)-thione. m/e+ 367 for C20H19N4S [M+H]+; 1H-NMR (300 MHz, CDCl3) δ 8.54 (d, J=4.8 Hz, 2H), 7.94 (d, J=4.8 Hz, 1H), 7.74 (m, 2H), 7.56 (d, J=9.0 Hz, 1H), 7.27 (dd, J=4.2, 7.8 Hz, 2H), 7.05 (m, 2H), 4.94 (s, 2H), 2.40 (s, 3H), 2.33 (s, 3H) ppm.

Provenance & Evidence